The study was carried out through measuring the temperature and humidity of the indoor/outdoor space and the distribution of interior thermal condition, and investigating the effect of loess materials on human body. The purpose of this study is to analyze the change of dry bulb temperature and relative humidity and correlation of thermal reaction of human body with ASHRAE (American Society of Heating, Refrigerating and Air-conditioning) comfort chart in the loess interior space. In the view point of biomedical sciences, loess interior space provides optimum thermal conditions for human thermal sensation.