In this study, the operation strategy of the radiant floor cooling is evaluated in terms of indoor environmental conditions and energy consumption through simulations using the TRNSYS comparing the existing cooling operation. The operation strategy during continuously operated for cooling is proposed that a representative room had additional equipments and other rooms were operated with only a radiant floor cooling system and that system and control method for cooling are varied with period while intermittently operated for cooling. Specifically, when there are no people in the room, rooms were operated by only radiant floor cooling system using cooling storage and when people are occupied, rooms were operated by dehumidification and supplementary cooling device with radiant floor cooling system. The results of this study show that proposed operation strategy can stably maintain the set room air temperature and can reduce the energy consumption compared to the existing cooling method during continuously operated for cooling. While intermittently operated for cooling, the difference of set room air temperature by proposed operation strategy does not happen, satisfying comfort standards and the radiant floor cooling can expect to supply stable electric power because of decreasing demand for peak electric power of energy consumption.