On the relationship between the red tide occurrence and the oceanographic factors in the middle coastal area in the South Sea of Korea, the favorable oceanographic conditions for the red tide formation are considered as follows； the calm weather increases sea water temperature in summer and early-fall which the red tide occurs frequently, and the heavy precipitation brings some riverine water to ween: low salinity, high suspended solid, low phosphorus and high nitrogen, respectively. We decided the potential areas in the coastal zones vulnerable to the red tide occurrence based on the limited factors controlling the growth of phytoplankton. By using GIS through the overlap for three subject figures (phosphorus, nitrogen and suspended solids), it was founded that the potential areas are the Yeosu∼Dolsan coast, the Gamak bay, the Namhae coast, the Narodo coast, the Goheung and Deukryang bay. This result has very well coincided to the results of the satellite and in-situ data.