Spaceborne earth observation or astronomical payloads often use Cassegrain-type telescopes due to the limits in mass and volume. Precision optical alignment of such a telescope is vital to the success of the mission. This paper describes the simulated optical alignment methods using interferograms, wavefront error, and reverse-optimization method for different levels of alignment accuracy. It concludes with the alignment experiment results of a Cassegrain type spaceborne camera with 300mm entrance pupil diameter.