Loop thermosyphon(LTS) has many good characteristics such as low thermal resistance, no power consumption, noiseless operation and small size. To investigate the overall performance of LTS, we have performed various experiments varying three parameters: input power of the heater, working fluid(water, ethanol, FC3283) and filling ratio of the working fluid. At a combination of these parameters, temperature measurements are made at many locations of the LTS. The temperature difference between the evaporator and the condenser is used to obtain the thermal resistance. In addition, flow visualization using a high speed camera is carried out. The thermal resistance is not constant. It is lower at higher input power, which is one of the distinct merits of LTS. Flow instabilities are frequently observed when changing the working fluid, the input power and the filling ratio. The results show that the LTS can be readily put into practical use. Future practical application in electronic cooling is recommended.