The Institute of Medicine of the National Academies Food and Nutrition Board in conjunction with Health Canada recently released the sixth in a series of reports on dietary reference values for the intake of energy and macronutrients. This paper discusses the Dietary Reference Intakes (DRIs) for energy and physical activity. Several new approaches were used with the DRIs for the macronutrients. Those discussed in this paper include: $.$Estimated Energy Requirements (EER) at four levels of energy expenditure based on doubly labeled water measurements of total energy expenditure (TEE). $.$Recommendations for levels of physical activity to decrease the risk of chronic disease.