Drying Shrinkage has much complexity as it has relations with both internal elements of concrete and external factors. Therefore, experiments on Concrete Drying Shrinkage are carried out in this study under simplified circumstances applying temperature & Humidity test chamber which enables constant temperature and humidity. Comparative analyses have been made respectively according to the consequences aiming at modelling for prediction of Concrete Drying Shrinkage and making out measures to reduce it. Strain Rate of Drying Shrinkage of concrete under the condition of dry air appears to rise by about 20%-30% in proportion as the temperature rises 5℃ when the humidity was held below 10% compared under the condition of dry temperature & Humidity test chamber. Strain Rate of Drying Shrinkage in pit sand concrete increased 20% higher than measured when in river sand under the condition of 90-day material age. A general formula with two variables is derived as follow ε= α₁＋β₁χ₁＋β₂χ₂＋β₃χ²₁＋β₄χ₁χ₂＋β₅χ²₂. and also graphed in 3 dimensions, enabling to apply to actual design and predict Strain Rate of Drying Shrinkage in concrete. The results of prediction of Rate of Drying Shrinkage by Response Surface Analysis are as follows. The coefficient of correlation of Drying Shrinkage in Concrete was over 90%