- 수종 항암 처방의 조합에 따른 면역조절 작용에 관한 연구
- ㆍ 저자명
- 백명현,박종대,이용구,김동희,Baik. Myung hyun,Park. Jong Dae,Lee. Yong Koo,Kim. Dong Hee
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2004년|18권 1호|pp.157-166 (10 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
In order to understand the anti-carcinogenic effects of Boo-jung-bae-bon-bang(扶正培本方)-B1), Hwal-hyul-hwa-eo-bang(活血化瘀方-B2), Cheong-youl-hae-dok-bang(淸熱解毒方-B3), prescriptions of individual B1, B2, and B3 treatments or combined treatments (B4; B1+B2, B5; B1+B3, B6; B1+B2+83, B7; B2+83) were applied to cultured cancer cell lines. The major findings on their anti-cardnogenic effects in terms of mechanism and synergistic interactions are summarized below. Results of cytokine gene expression analyses are summarized as follows; IL-2 gene expression was increased by B1 and B6 treatments, IFN-v gene expression increased by B3, B1, B6, and 85, and CD28 gene expression increased by B1 and B5. IL-4 expression was not affected by any treatments. In the FACS analysis, increases in numbers of immunoreactive CD3+/CD25+ T cells by B1 and B5 treatment, CD3+/CD69+ T cells by B1, B3, B5, and B6 treatments, CD19+/CD44+ B cells by B1 and B6 treatments were observed when compared to the corresponding non-treated control groups.