Industrial structure systems may have nonlinearity, and are also sometimes exposed to the danger of random excitation. This paper proposes a method to analyze response and reliability design of a complex nonlinear structure system under random excitation. The nonlinear structure system which is subjected to random process is modeled by finite element method. The nonlinear equations are expanded sequentially using the perturbation theory. Then, the perturbed equations are solved in probabilistic methods. Several statistical properties of random process that are of interest in random vibration applications are reviewed in accordance with the nonlinear stochastic problem.