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An Improved Method for Constructing Confidence Interval of Median : Small Sample Case
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  • An Improved Method for Constructing Confidence Interval of Median : Small Sample Case
  • An Improved Method for Constructing Confidence Interval of Median : Small Sample Case
저자명
Park. Sang-Gue,Choi. Ji-Yun
간행물명
한국데이터정보과학회지
권/호정보
2004년|15권 4호|pp.973-980 (8 pages)
발행정보
한국데이터정보과학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Phase I clinical trials are often pharmacologically oriented and usually attempt to find the best dose of drug to employ. However, other purposes like determination of sizes and types of side effects and toxicity and organ system involved are equally important. Estimation of treatment effects or side effects is usually ignored since it is usually based on too small sample, even though Phase II clinical trials would be designed based on the Phase I studies. Statistical methods for constructing the approximate confidence interval for population median in case of small sample are considered and an improved method is proposed. The proposed estimator is compared with current methods through simulation studies.