This study was conducted to investigate the delivery pattern of volatile organic compounds(VOCs) in mainstream smoke generated by the combustion of a different ventilated cigarette. To compare the delivery pattern and the concentration of VOCs in mainstream smoke, the six different ventilated cigarette was manufactured and analyzed VOCs using the GC/MS. As a result of this experiments, cambridge filter used to trap the particulate matter in mainstream smoke did not affect on the trapping of VOCs components, and two impinger method among the trapping methods was the best condition to trap VOCs from mainstream smoke. As the slope of the delivery of VOCs such as isoprene, acrylonitrile and toluene were higher than 1, but that of benzene was lower than other VOCs.