Purpose: The purpose of this study was to identify the effects of Guided Imagery on the stress and anxiety of nursing students in clinical practice. Method: The research design was a nonequivalent control group pretest-posttest design. The data were collected from the 20th of June to the 11th of July 2003. The objects of this study were 32 nursing students of college(16 for the experimental group, 16 for the control group). The instruments used in this study were State Trait Anxiety Inventory, the stress scale developed by Choi(1991). The guided imagery was provided through audiotapes to the subjects for 8 minutes, a time for 5 days. The pretest was given before the therapy to measure variables for both groups and the posttest was performed after intervention. The data were analyzed by the SAS program using t-test. Result: The results of this study are as follows. The stress scores of students were decreased in the experimental group, but were not significantly different between the experimental group and the control group after the guided imagery. The anxiety scores of students were significantly different between the experimental group and the control group after the guided imagery. Conclusion: The guided imagery can be suggested as an effective nursing intervention to reduce the anxiety. Further studies to identify the effects of stress reduction according to the frequency of the guided imagery can be needed.