We report an important and useful method for preparing ${omega}-sulfonated$ polystyrene-stabilized cadmium sulfide (CdS) nanoclusters. The ${omega}-sulfonated$ polystyrene $(M_n;=;5000;g/mol)$ was prepared successfully through chain-end sulfonation of poly(styryl)lithium using 1,3-propanesultone; the resulting polymer was used successfully as a polymeric stabilizing agent for the preparation of semiconductor CdS nanoclusters by reduction of cadmium acetate in a mixture of toluene and methanol (9:1, v/v). The nanoclusters that formed were characterized by a combination of transmission electron microscopy, X-ray diffraction, and UVN is spectroscopic analysis. The ${omega}-sulfonated$ polystyrene-stabilized CdS nanoclusters synthesized in this study exhibited the cubic phase (zinc-blende phase) structure in the range of 2-8 nm.