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H2O2/HCl 처리한 Ti 임플란트의 생체활성 평가
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  • H2O2/HCl 처리한 Ti 임플란트의 생체활성 평가
저자명
유재선,권오성,이오연,이민호,송기홍,Yue. J. S.,Kwon. O. S.,Lee. O. Y.,Lee. M. H.,Song. K. H.
간행물명
한국재료학회지
권/호정보
2005년|15권 5호|pp.353-360 (8 pages)
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한국재료학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Surface treatment play an important role in nucleating calcium phosphate deposition on surgical Ti implant. Therefore, the purpose of this study is to examine whether the precipitation of apatite on cp-Ti and Ti alloys are affected by surface modification in HCl and $H_2O_2$ solution. Specimens were then chemically treated with a solution containing 0.1 M HCl and 8.8M $H_2O_2$ at $80^{circ}C$ for 30 mins, and subsequently heat-treated at $400^{circ}C$ for 1 hour. All specimens were immersed in the HBSS with pH 7.4 at $36.5^{circ}C$ for 15 days, and the surface was examined with XRD, SEM, EDX ana XPS. Also, pure Ti, Ti-6Al-4V and Ti-6Al-7Nb alloy specimens with and without surface treatment were implanted in the abdominal connective tissue of mice for 4 weeks. All specimens chemically treated with HCl and $H_2O_2$ solution have the ability to form a apatite layer in the HBSS which has inorganic ion composition similar to human blood plasma. The average thickness of the fibrous capsule surrounding the specimens implanted in the connective tissue was $38.57;{mu}m,;62.27;{mu}m;and;45.64;{mu}m$ in the cp-Ti, Ti-6Al-4V ana Ti-6Al-7Nb alloy specimens with the chemical treatment respectively, and $52.20;{mu}m,;75.62;{mu}m;and;66.56;{mu}m$ in the commercial specimens of cp-Ti, Ti-6Al-4V and Ti-6Al-7Nb without any treatment respectively. The results of this evaluation indicate that the chemically treated cp-Ti, Ti-6Al-4V ana Ti-6Al-7Nb alloys have better bioactivity and biocompatibility compared to the other metals tested.