ISO 9000 quality standards families were established in 1987 and have been started to implement Korean industry since early 1990s. ISO 9000 standards families of 1987 were revised in 1994 and 2000, respectively, by request of world wide certification bodies and industry quality experts. This article reviews the necessity of ISO 9001 :2000 revision, quality management principles behind it, and benefits that ISO 9001: 2000 could bring. We summarize responses of foreign industry that ISO 9001: 2000 has been implemented. Survey questionnaire for 23 requirements of ISO 9001: 2000 from manufacturing companies of Busan and Kyungnam provinces are collected. Research hypotheses that there is any difference in quality management system practical application due to company size and implementation motivation are tested using SPSS. Finally, recommendations are provided for operating successful quality management system.