The aim of this study is to relieve the poor ventilation problem of the diesel locomotive engine load test building, located in an urban area. This paper evaluates the ventilation performances of the studied load test building based on the temperature measurement experiment and the computational fluid dynamics (CFD) during the engine load test. The temperature rise caused by the radiator blower of the building was turned out to be the main cause of disturbing the thermal conditions of the building. The indoor temperature distributions simulated by Fluent were validated with the temperature measurement results obtained from the studied building. The simulation results indicated that the comfort condition of this building was poor We suggested several remedial changes in the duct structure of this building for the improvement of the comfort conditions. In addition, a prototype drawing combining several improved design options was proposed. and then the simulation of the temperature distribution in the proposed prototype was performed. The result indicated that the indoor thermal condition of this proposed building was improved when compared with that of the current building.