The purpose of this study was to find how hybrid fashion and make-up responses to multiculturalism condition and how expression of hybrid. Today, every culture has taken on the compromise form by means of the cultural difference, variety, and pluralism according to the internationalization and the advance. In accordance with this current of the times, this study observed the hybrid found in the multiculturalism of the 21th century. The expression of hybrid in multiculturalism of contemporary fashion and make up combination of difference. Second, the society development and a generalized knowledge of multiculturalism and hybrid and history of make up. Third, characteristic of fashion about multiculturalism and characteristic of fashion about hybrid classify a divide into five according to fashion trend. Oriental and western of hybrid, the past and the present of hybrid, high society and the lower classes of hybrid, the main current and non mainstreamers of hybrid, the present and the future of hybrid. Fourth, characteristic of make up about multiculturalism and characteristic of make up about hybrid classify a divide into five according to fashion trend. Oriental and western of hybrid, the past and the present of hybrid, high society and the lower classes of hybrid, the main current and non mainstreamers of hybrid, the present and the future of hybrid take measures too.