The latest scientific highlights obtained with the Subaru telescope are given together with its current status and on-going instrumentation. We have been successfully operating the telescope and 8 observatory instruments (including an adaptive optics system) since January 1999, when the first light was accomplished. Open-use of Subaru began in December 2000. Subaru has a unique capability of its prime focus among other 8-10 meter class telescopes and has an excellent imaging performance as a result of its sophisticated active optics combined with the high stability of the sky at Mauna Kea. Scientific highlights are given on the discoveries of the most distant galaxies, spiral structure on a protoplanetary disk around AB Aur, and planetesimal belts in the debris disk around $eta$ Pic. Brief summaries are given for three new instruments: the Multi-Object Infrared Camera and Spectrograph (MOIRCS), 188 element adaptive optics system, and Fiber Multi-Object Spectrograph (FMOS)