In this study, the evaluate characteristics of fire and explosion of MEK-PO are subjected to spontaneous ignition, flash point and explosion hazard. The minimum ignition temperature and instantaneous ignition temperature for MEK-PO were $188.5^{circ}C;and;230^{circ}C;at;225{mu}L$. In addition The flash point for MEK-PO was obtained at $49^{circ}C$. Furthermore, the maximum explosion pressure and the maximum explosion pressure rising velocity: using MCPVT (mini cup pressure vessel tester) were $10.82kgf/cm^2;and;33.72kgf/cm^2{cdot}s$.