- 보중익기탕가미방(補中益氣湯加味方)이 흰쥐의 성장과 학습 및 기억에 미치는 영향
- ㆍ 저자명
- 민상연,김장현,장규태,Min. Sang-Yeon,Kim. Jang-Hyun,Chang. Gyu-Tae
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2005년|19권 2호|pp.434-440 (7 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
This study was conducted to find out the effect of Bojungikgitanggamibang(BIT) on growth, learning and memory of rats. The effects of BIT on learning and memory performance were examined in normal or memory impaired mice by using water maze task. Memory was impaired by 192 saporin. Body weight and growth of bone and tail of sample group were not significant compared with those of control groups. Acquisition test of water maze revealed that acqusitive ability of sample group significantly improved on 4,5th day compared with control group, while retentive ability of sample group was not significant. ChAT cell numbers of medial septum of sample group was significant compared with control group, and so was those of CA1, CA2 parts of hippocampus. On ChAT cell numbers of hippocampus, in CA2 part. These results suggest that BIT has an improving effect on the impaired learning through the effects on memory registration and retrieval.