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Methoxychlor투여 흰쥐에 있어서 복분자 술이 Testosterone에 미치는 효과
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  • Methoxychlor투여 흰쥐에 있어서 복분자 술이 Testosterone에 미치는 효과
저자명
이성일,황인수,허진,임채웅,주성민,전병훈,백병걸,Lee. Sung-Il,Whang. In-Soo,Hur. Jin,Lim. Chae-Woong,Ju. Sung-Min,Jeon. Byung-Hun,Baek. Byeong-Kirl
간행물명
동의생리병리학회지
권/호정보
2005년|19권 3호|pp.656-661 (6 pages)
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대한동의생리학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

The study was conducted to investigate per oral (PO) effects of Black raspberry wine on testosterone levels in Sprague-Dawley rats oral administrated with Methoxychlor in order to establish the experimental clinical model for evaluating the influences on the sexual hormones of SD-Rat administrated with Methoxychlor(MET), it was dissolved in acetone and olive oil (1:19), which was administrated orally at doses of 200mg/kg body weight/ day for 7days. Black raspberry wine of 13% alcohol concentration, was prepared from ripen fruits of Rubus coreanus fermented with Saccharomyces cervisiae. PO administration of Black raspberry wine for 15 week produced dramatic increases of serum testosterone levels. Increase in the testosterone level was observed, using gamma counter with 125I testosterone, starting from 1 week post administration. Maximum increase in testosterone level was observed at 4 week post administration, 5.18${pm}$0.76ng/mL, which was 10.1 times higher than before and at 15 weeks post administration it was recorded as 1.67${pm}$0.19ng/mL indicating Black raspberry wine as an effective phyto-testosteronic beverage of the future.