Objective : This study was carried out to investigate the differences of mental illness between Korea and China in oriental medicine Method : Several main texts in oriental medicine and articles related with topic were collected and inquired. Result : There are some differences of mental illness between Korea and China in oriental medicine. Brain is more important than heart in psychophysiology of chinese medicine, and blood stasis is a main pathologic factor of mental illness. They use not only Ohaeng(five elements) theory, but also Yin-yang theory in oriental psychotherapy. Conclusion : It seems that materialism and western medicine had some influences on modern chinese medicine. On the other hand, There are respect for traditional theory and creativity in Korean medicine represented by Dongeuibogam(東醫寶鑑) and Sasang constitutional medicine.