Recently the building of ultra large container ship are discussed among ship building companies and ship operating company who have a tendency to pursue the advantage of large scale of economy. These tendency will be continued for the time being, if ship-building skill and economical efficiency are available. As the enlargement of container ship size becomes hot issues in ship-building markets, the needs for re-arrangement of accommodation house in large container ship are proposed carefully in some researches. This study examined economical efficiency of re-arrangement of accommodation house in ultra large container ship. The separation between accommodation and engine room is proposed through out drawing works in initial design stage and we examined the merits and demerits of the separation in the view of economical efficiency. The RFR(Required Freight Rate) is considered as the objective function to evaluate the re-designed vessel. The economical benefits are analyzed in the view of ship operator and shipyard respectively.