This study presents the thermal cracking on a commercial vehicle ventilated brake disk. Distributions of temperature and thermal stress of the disk were analysed, using FEM analysis, under the several driving conditions with actual vehicle specifications. The results from the fatigue tests on the disk material were compared with those from FEM analysis. In case of deceleration of 0.6 g with initial vehicle speed of 97, 140, and 160 km/h, the maximum compressive stress at the disk surface of disk due to braking was 224, 318, and 362 MPa, respectively. It was estimated that each damage fraction of 0.00005, 0.00050, 0.00136 per full stop was imposed on the brake disk in case of deceleration of 0.6 g with initial vehicle speed of 97, 140, and 160 km/h, respectively.