The effects of the low temperature plasma and chitosan treatments on the shrink resistant properties and hand of wool fabrics have been studied. When the plasma treatment was carried out on the wool fabrics, the cuticle of the wool fabrics seemed to be damaged; especially at 150 W power, it was observed that the scales were broken. Therefore the structural changes of the wool fabrics decreased the felting shrinkage of the wool fabrics. Howerver, the plasma treated wool fabrics showed harsher handle compared to untreated wool fabrics. When the plasma pretreatment was applied on the wool fabrics, then water soluble chitosan was coated on the surface of wool fibers uniformly, the shrink resistance of the wool fabrics was enhanced. The plasma-chitosan treatment also affected the mechanical properties and hand values of the wool fabrics.