A nonlinear time-domain strip theory for vertical wave loads and ship responses is to be investigated. The hydrodynamic memory effect is approximated by a higher order differential equation without convolution. The ship is modeled as a non-uniform Timoshenko beam. Numerical calculations are presented for the S175 Containership translating with the forward speed in regular waves. The approach described in this paper can be used in evaluating ship motions and wave loads in extreme wave conditions and validating nonlinear phenomena in ship design.