For blood cockle Tegillarca granosa acclimated to winter and summer seasons, survival, temperature tolerance and physiological changes at different individual size were investigated for their temperature tolerances by increasing and decreasing temperature at a rate of 1, 2 and $3^{circ}C/day$. The survival rate of adults and juveniles T. granosa acclimated to winter temperatures began to decrease from $32^{circ}C$ and all experimental animals died between $37-39^{circ}C$. In the case of animals acclimated to summer temperatures, the survival rates of adults and juveniles began to decrease from $35^{circ}C$, and all died at temperatures between $40-44^{circ}C$. The upper $LT_{50}$ was $27.72^{circ}C$ for adults and $28.36^{circ}C$ for juveniles. On the other hand, when the temperature was decreased from $4^{circ}C;to;0^{circ}C$ in order to investigate lower temperature tolerances, the survival rate of T. granosa was more than $70\%;at;2^{circ}C$ for 25 days. Lower L T 50 was $2.09^{circ}C$ for adults and $2.34^{circ}C$ for juveniles. There was no effective difference in temperature tolerance between adults and juveniles. Filtration and respiration rates of T. granosa showed a similar aspect with increase and decrease of temperature. Filtration and respiration rates exhibited irregular conditions of a broken biological rhythm as the group acclimated to winter $(10 ^{circ}C)$ and summer $(25^{circ}C)$. In the case of decreasing temperature, filtration and respiration rates of T. granosa reduced to a minimum below $6^{circ}C$