The fatigue analysis and lifetime evaluation are very important in design procedure to assure the safety and reliability of the rubber components. Fatigue lifetime prediction methodology of the rubber component was proposed by incorporating the finite element analysis and fatigue damage parameter from fatigue test. Finite element analysis of 3D dumbbell specimen and rubber component were performed based on a hyper-elastic material model determined from material test. The Green-Lagrange strain at the critical location determined from the FEM was used for evaluating the fatigue damaged parameter of the natural rubber. Fatigue life of the rubber component are predicted by using the fatigue damage parameter at the critical location. Predicted fatigue lifes of the rubber component agreed fairly well the experimental fatigue lives.