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심혈관 계통의 조절을 통한 신장 기능에 미치는 오미자의 효과
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  • 심혈관 계통의 조절을 통한 신장 기능에 미치는 오미자의 효과
  • Effects of Schizandriae fructus Extract on the Renal Function by Cardiovascular Regulation
저자명
박성혜,함태식,Park. Sung-Hye,Hahm. Tae-Shik
간행물명
東아시아食生活學會誌
권/호정보
2005년|15권 5호|pp.558-565 (8 pages)
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동아시아식생활학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

In this study, Schizandriae fructus which has been used in oriental medicine and folks remedy, was studied to apply to functional foods and oriental medicinal cuisine. The aim of this experiments was to investigate the effects of Schizandriae fructus water extract(SFE) on the renal function, plasma renin activity, plasma levels of aldosterone and arterial natriuretic peptide(ANP) in rats. Spargue-Dawley rats weigh 200g, were randomly assigned to 3 groups such as basal diet only(BDG), basal diet with $0.5{mu}L/g$ SFE(LAG) and basal diet with $1.0{mu}L/g$ SFE(HAG). The results were as follows. Water balance decreased significantly after administration for 2 weeks compared with the control period in HAG. Urine volume increased significantly after administration for 1 week compared with the control period in LAG and HAG. Urinary excretion of sodium increased significantly after administration for 1 week and for 2 weeks compared with the control period in LAG and HAG. Urinary excretion of creatinine increased significantly after administration for 2 weeks compared with the control period in HAG. Plama levels of ANL decreased significantly after administration of $SFE(0.5{mu}L/g)$. Plasma levels of aldosterone decreased significantly after administration of $SFE(1.0{mu}L/g)$. There results indicated that Schizandriae fructus can improve the renal function through increased urine volume and sodium excretion. These results imply that SFE could be used as a potent food resource for diet therapy or clinical nutrition.