- 서울지역 영아 설사환자로부터 분리한 로타바이러스의 유전자형 및 G9 VP7 유전자 염기서열
- ㆍ 저자명
- 김효헌,강성훈,김원용,Kim. Hyo-Heon,Kang. Sung-Hoon,Kim. Won-Yong
- ㆍ 간행물명
- Journal of bacteriology and virology : JBV
- ㆍ 권/호정보
- 2005년|35권 1호|pp.67-74 (8 pages)
- ㆍ 발행정보
- 대한미생물학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
Genotyping of human rotaviruses was performed using 55 rotavirus-positive samples collected from 90 young children with diarrhea at Chung-Ang University Yongsan Hospital between December 2001 and May 2002. G typing of the VP7 protein showed that G2 was the most dominant circulating genotype (32.8%) followed by G1 (21.8%), G4 (12.7%), G3 (10.9%), G9 (1.8%) and a combination of G2/G3 (7.3%). P typing of the VP4 protein revealed that P[4] (60.0%) was the most prevalent strain, followed by P[6] (25.5%), P[8] (3.6%) and P[9] (1.8%). Seven samples (12.7%) for G type and 5 samples (9.1%) for P type remained untypable. The most predominant G-P combination was G2P[4] (29.1 %), which is one of the most commonly observed type worldwide. A G9 serotype strain identified in this study shared more than 97% nucleotide homologies with 18 foreign G9 isolates. Therefore, incorporation of G9 rotavirus into current vaccine formula should be considered.