Recent warnings indicate that there is a potential risk of massive earthquake. These earthquakes could produce large-scale tsunamis. Consideration of the effect of Tsunami to the moored ship is very important bemuse it brings the loss of life and vast property damage in a viewpoint of ship operations within a harbor. If a tsunami occurs, a ship in a harbor may begin drifting in case of ship entering and departing harbor, and breakage of mooring rope and drifting of moored ship are happened. And extremely serious accident, such as stranding and collision to a quay, might occur. On the other hand, since the tsunami consists of approximately component waves of several minutes, there is a possibility of resonance with the long period motion of mooring vessel. As the speed of Tsunami is much faster than tidal current in a harbor, a strong resisting force might act on the moored ships. In this paper, the numerical simulation procedure in the matter of ship motions due to the attack of large-scale tsunamis are investigated and the effects on the ship motions and mooring loads are evaluated by numerical simulation.