Purpose： This study compared lifestyles of middle school students with and without atopic dermatitis in order to obtain the baseline information for health education. Methods： This study involved 256 students from 20 middle schools in Busan who suffered from atopic dermatitis and 231 students from 2 middle schools in Busan who did not have atopic dermatitis. Results： Students with atopic dermatitis had a lower family income (탑=16.99, p<.001) and were more likely to come from a nuclear family (탑=10.28, p<.001) than control students. 98% of the students with atopic dermatitis had several skin symptoms. 78.5% of students with atopic dermatitis reported experiencing difficulties in their daily because of their condition. Students with atopic dermatitis took shorter baths and used soap less frequently than the students in the control group. The students with atopic dermatitis cleaned their houses and bedclothes more often than normal students in an attempt to remove cockroaches and house-dust mites. Students with atopic dermatitis also ate fast and instant foods more often than normal students. Conclusions： Some lifestyle differences exist between students with and without atopic dermatitis. Therefore, education and guidance may be important to promote good health and improve lifestyle quality.