Purpose: This study was to examine the relationship between psychosocial distress and health promoting behaviors of middle-aged women. Methods: The subjects consisted of 278 women between the ages of 40 and 60 years in the Seoul-Kyunggi region. Data collection was conducted through the use of questionnaires. The instruments for this study were psychosocial distress(45 items) and Health promoting behaviors(43 items). Results: The average item score for psychosocial distress was high at 96.5, and the health promoting behaviors were moderate at 139.8. The psychosocial distress was significantly different according to age, education, marriage status, menstruation status, satisfaction of marriage. The health promoting behaviors was significantly different according to religion, education, menstruation status, satisfaction of marriage. Negative correlations were observed between psychosocial distress and health promoting behaviors(r=-.43, p=.000). Conclusion: These findings help to clarify relationships between relationship between psychosocial distress and health promoting behaviors of middle-aged women. Therefore, the result of study provide clues for promoting health in middle-aged women.