The objective of this study is to find the optimal thrust condition and wing loading of a vertical take-off and landing (VTOL) fixed-wing aircraft through a single engine failure analysis during landing approach and an analysis of transition flight. The aircraft analysis modules used in the study are based on the aircraft synthesis program. To achieve the computing infrastructure for aircraft design and analysis, the EMDIOS was employed as a design framework, which is a semi-completed application program and ready to customize. Simulation results reveal the most critical height at the event of single engine failure is approximately 40 ft. And, in order to avoid a significant loss in altitude during the transition, the thrust to weight ratio must be kept high, while both the engine tilt speed and the wing loading must be kept low, as confirmed by the analysis results.