The purpose of this paper is to examine some aspects of international collaboration in the age of digital technologies. First, the paper describes the longitudinal structure of collaborative pattern among the 10 East-Asian countries based on their frequency of co-authoring SCI journal articles in the year 2001-2003. Second, a focus interview was made to explore the way in which new digital technologies such as the Internet have changed a research practice in the field of science, technology, and innovation. This research found that Japan and China are preferred as the number one collaborator by other Asian countries. Their share of international collaboration with other Asian countries has been increasing in three years. The results of indepth interview with a scholar suggest that digital network technologies have several advantages enabling individual and institutional actors to collaborate with each other effectively in terms of knowledge management as well as information exchange.