Purpose : To evaluate the effect of herb-medicine on seminal parameters in male infertility patients. Methods : 25 patients were enrolled in this study. They were taken herb-medicine three times a day after meals for 2-5months. Semen analysis or CASA were taken on baseline and post-treatment. Results : The result were as follows : (1) No statistical differences in seminal volume were found. (2) The mean${pm}$SD of sperm concentration was increased from $51.39{pm}37.80{ imes}10^6$ to $75.99{pm}50.34{ imes}10^6/ml$ alter treatment(P<0.05). (3) The mean${pm}$SD of motility was increased from 20.22${pm}$10.75% to 34.02${pm}$21.36% after treatment(p<0.01). Conclusion : Herb-medicine can be effective on male infertility.