The purpose for this study is to identify the effects of nonnutritive sucking and facilitated tucking as a pain management during painful heelstick procedure. This study was a repeated measurement design. Data were collected from Sep. 15, to Oct. 20, 2005. According to the criteria twenty seven high risk infants were selected from the NICU of university hospital. The behavioral state were evaluated with the PIPP(Prematures Infants Pain Profile. PIPP, heart rate, saturation were observed without versus with nonnutritive sucking and tucking care. Statistic analysis was conducted with a wilcoxon nonparametric test. The results of this study were as follows. Pina behavior responses in nonnutritive sucking and tucking cases were lower than without treatment(Z=-4.430, p=.000), Heart rate and heart rate recovery time in nonnutritive sucking and tucking cases were attenuate decrease in heart rate(Z=-2.694, p=.005) and statistical significant differences in periods (Z=-4.229, p=.000). But, Saturation was no significant differences(Z=-3.230, p=.000). In conclusion, the application of nonnutritive sucking and tucking as an pain relieg for high risk infants is nursing intervention in pain management ar heelsticks.