Seismic random responses due to the wave passage effect are extensively investigated by using the pseudo excitation method (PEM). Two examples are used. The first is very simple but also very informative, while the second is a realistic suspension bridge. Numerical results show that the seismic responses vary significantly with wave speed, especially for low velocity or large span. Such variations are not monotonic, especially for flexible structures. The contributions of the dynamic and quasi-static components depend heavily on the seismic wave velocity and the natural frequencies of structures. For the lower natural frequency cases, the dynamic component has significant effects on the dynamic responses of the structure, whereas the quasi-static component dominates for higher natural frequencies unless the wave speed is also high. It is concluded that if insufficient data on local seismic wave velocity is available, it is advisable to select several possible velocity values in the seismic analysis and to choose the most conservative of the results thus obtained as the basis for design.