This paper describes the theoretical background and underlying principles behind the American Institute of Steel Construction Load and Resistance Factor Design (AISC LRFD) Specification for the analysis and stability design of steel frames. Various analysis procedures that can take into consideration the effects of member instability, frame instability, member-frame interaction, geometric imperfections, and inelasticity are reviewed. Design approaches by which these factors can be incorporated in the design of steel moment frames are addressed. Current specification guidelines for member and frame design in the U.S. are summarized. Examples are given to illustrate the validity of the design equations. Some future directions for the analysis and stability design of steel frames are discussed.