- 비침습적인 전기자극이 임프란트의 골융합에 미치는 영향;토끼경골에서의 조직계측학적 평가
- ㆍ 저자명
- 손성배,박진우,서조영,Sohn. Sung-Bae,Park. Jin-Woo,Suh. Jo-Young
- ㆍ 간행물명
- 대한치주과학회지
- ㆍ 권/호정보
- 2005년|35권 3호|pp.635-648 (14 pages)
- ㆍ 발행정보
- 대한치주과학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The procedure that enhances osteogenesis and shortens the healing period is required for successful implant therapy. It has been introduced that osteogenesis is enhanced by the generation of electric field. Many researchers have demonstrated that application of electric and electromagnetic field promote bone formation. It also has been shown that electrical stimulation enhances peri-implant bone formation. Recently, several investigators have reported that noninvasive electrical stimulation using negatively charged electret such as polytetrafluoroethylene(PTFE) promotes osteogenesis. Therefore, we were interested in the effect of noninvasive electrical stimulation using negatively charged electret on the periimplant bone healing. After titanium implant were installed in the proximal tibial metaphysis of New Zealand white rabbit, negatively charged PTFE membrane fabricated by corana dischage was inserted into the inner hole of the experimental implant and noncharged membrane was applied into control implant. After 4 weeks of healing, histomorphometric analysis was performed to evaluate peri-implant bone response. The histomorphometric evaluations demonstrated experimental implant tended to have higher values in the total bone-to-implant contact ratio(experimental ; $49.9{pm}13.52%$ vs control ; $37.5{pm}19.44%$) , the marrow bone contact ratio(experimental ; $34.94{pm}13.32%$ vs control ; $24.15{pm}13.69%$), amount of newly formed bone in the endosteal region(experimental ; $1.00{pm}0.30mm$ vs control ; $0.61{pm}0.24mm$) and bone area in the medullary canal(experimental ; $13.55{pm}4.98%$ vs control ; $9.03{pm}3.05%$). The mean values of the amount of newly formed bone(endosteal region) and bone area(medullary canal) of the experimental implant demonstrated a statistically significant difference as compared to the control implant(p<0.05). In conclusion, noninvasive electrical stimulation using negatively charged electret effectively promoted peri-implant new bone formation in this study. This method is expected to be used as one of the useful electrical stimulation for enhancing bone healing response in the implant therapy