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LC/MS를 이용한 식육중 잔류 벤지미다졸계 구충제 분석법 연구
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  • LC/MS를 이용한 식육중 잔류 벤지미다졸계 구충제 분석법 연구
저자명
최은영,서형석,백귀정,허부홍,서이원,정동석,Choi. Eun-Young,Seo. Heyng-Seok,Baek. Kui-Jeong,Hur. Boo-Hong,Seo. Lee-Won,Joung. Dong-Suk
간행물명
韓國家畜衛生學會誌
권/호정보
2005년|28권 1호|pp.81-89 (9 pages)
발행정보
한국가축위생학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Recently, mass spectrometry coupled with liquid chromatography (LC/MS) has been a preferred technique for determination of organic compounds in complex matrixes. LC/MS provides a high degree sensitivity and specificity of the compounds of interest. The purpose of this study was to confirm analytical method of residual 6 benzimidazoles (thiabendazole, oxfendazole, mebendazole, albendazole, flubendazole and fenbendazole) in meat by LC/MS. Benzimidazoles were analyzed by LC/MS on XTerra $C_{18}$ column with 0.01% trifluoroacetic acid-acetonitrile (TFA) in a gradient mode as mobile phase, and that were identified by electrospray ionization with selected ion recording mode at 150-350 amu mass range. Residual benzimidazoles were extracted from tissue with ethylacetate, and elute benzimidazoles with $50\%$ acetonitrile. In the LC/MS analysis of benzimidazoles, signal to noise ratio was showed relatively high in the positive mode and special ion in the quality analysis was determined via $[M+H]^+$ and Fragment ions. A spectrum of benzimidazoles was showed from all 6 benzimidazoles