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The Effect of High Fat Diet on the Vasoendothelial Cell in Healthy Adults
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  • The Effect of High Fat Diet on the Vasoendothelial Cell in Healthy Adults
  • The Effect of High Fat Diet on the Vasoendothelial Cell in Healthy Adults
저자명
김재영,Kim. Jai-Young
간행물명
Journal of experimental & biomedical sciences
권/호정보
2005년|11권 1호|pp.79-84 (6 pages)
발행정보
대한의생명과학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

This study was performed to determine whether postprandial hypertriglyceridemia can affect the endothelial function. Endothelial function was assessed by flow-mediated endothelium-dependent brachial artery vasodilation (FMD) which was defined as percentile changes of diameter. Thirty one patients were enrolled in this study. The serum lipid profiles and FMD were measured at fasting, and after low fat and high fat meals. The serum triglycerides at 2 hours after a high fat meal were significantly increased compared to those measured at 2 hours after a low-fat meal and at fasting state (P<0.05). The FMD was transiently decreased (P<0.0001) from $11.4{pm}3.2\%$ at fasting state to $6.5{pm}2.5\%$ after a high-fat meal. The FMD was inversely related with postprandial hypertriglyceridemia (P<0.05). In conclusion, this study may suggest that postprandial hypertriglyceridemia causes endothelial dysfunction.