Lipophorin (Lp) has an approximate native molecular weight of 730 kDa for Bombyx mori and consists of ApoLp-I and ApoLp-II with molecular weights of 250 kDa and 90kDa for B. mori and 230 kDa and 80 kDa for Hyphantria cunea and 230 kDa and 49 kDa for Lymantria dispar, respectively. Lipid in Lp was mostly composed of neutral lipid. Lp of B. mori maintains constant level during larval and pupal stages but greatly increases during adult stage in both male and female. Lp of H. cunea appeared in great amounts in protein yolk bodies of ovary when vitellogenesis is actively taking place and was present in testicular fluid but not in the peritoneal sheath and cysts of testis. ApoLp-III of B. mori has a molecular weight of 17 kDa and similar amino acid composition as those of other species Lp. H. cunea apoLp- III has a molecular weight of 18 kDa and was present in all stages and in the protein body of ovary and in the cyst of testis. ApoLp-III is synthesized in larval and adult fat body. cDNA sequence of Spodoptera litura apoLp-III encodes a 188 amino acid polypeptide including a 22 amino acid leader peptide. Galleria mellonella Lp receptor has an approximate molecular weight of 97 kDa and 110 kDa under non-reducing and reducing conditions, respectively and bound HDLp specifically. Lp receptor cDNA of G. mellonella showed th pattern of the VLDL receptor belonging to the LDL receptor family. The variant Lp receptors were expressed in the fat body of G. mellonella; one is a Lp receptor which lacks 84 bp of 0 - linked sugar domain and the other is a full length form of the Lp receptor. The Lp receptor from the fat body of G. mellonella was differently expressed depending on the tissue and the developmental stages with specific abundance in prepupal stage.