An unmanned aerial vehicle (UAV) is generally flied via a pre-planned flight path or real-time commands by an operator. To succeed in an assigned mission, analysis such as the line-of-sight analysis for communication between UAV and a ground data terminal should be performed. In this paper, various analysis algorithms which are performed by a ground control station in pre-flight and in-flight phases, are proposed for the safe flight of UAV. Note that the proposed algorithms can be applied to most UAV systems.