Objectives: The purpose of this study was to compare Taebaek(SP3) Sinmun(HT7), Daedon(LR 1) Yongcheon(KI1) on the Blood Pressure in Hypertensive RAT induced by 2K1C. Methods : This experiments was to investigate the effects of Herbal-Acupuncture at Taebaek(SP3) Sinmun(HT7), Daedon(LR1) Yongcheon(KIl) on the Blood Pressure, Cardiomegalic index, plasma levels of renin, plasma levels of atrial natriuretic peptide(ANP), serum levels of potassium, and serum levels of aldosterone in Hypertensive RAT induced by 2KlC. Results : The results were as follows. I. Blood Pressure was decreased significantly after Herbal-Acupuncture of Taebaek(SP3) Sinmun(HT7), Daedon(LR1) Yongcheon(KI1). II. Cardiomegalic index was decreased significantly after Herbal-Acupuncture of Daedon(LRl) Yongcheon(KI1). III. Plasma levels of atrial natriuretic peptide(ANP) was increased significantly after Herbal-Acupuncture of Taebaek(SP3) Sinmun(HT7), Daedon(LRl) Yongcheon(KIl). IV. Plasma levels of renin was decreased significantly after Herbal-Acupuncture of Taebaek(SP3) Sinmun(HT7), Daedon(LRl) Yongcheon(KI1). Conclusion : These results suggest that Blood pressure was decreased significantly after Herbal-Acupuncture of Daedon(LRl) Yongcheon(KI1) in Hypertensive RAT induced by 2K1C.