Objective : We aimed to study the relationship between the post-stroke depression and acceptance of the stroke. Method : For this study, 80 stroke patients were surveyed by using questionnaires for CES-D, acceptance for stroke, and social support. Result & Conclusion : 1. Acceptance for stroke varied inversely as the post-stroke depression. 2. The acceptance for the stroke appeased the negative influence caused by the stress of the stroke, and the post-stroke depression was biggest predictable variant. And location of the stroke were the predictable variants of the post-stroke depression. 3. When the gender, location of the stroke, motor power, age, period of stroke, and social support were controlled, the group with depression and the one without depression had a significant difference in the acceptance of the stroke.