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Antioxidant Constituents from the Leaves of Cedrela sinensis A. Juss
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  • Antioxidant Constituents from the Leaves of Cedrela sinensis A. Juss
  • Antioxidant Constituents from the Leaves of Cedrela sinensis A. Juss
저자명
Lee. Ik-Soo,Wei. Chun-Hua,Thoung. Phuong Thien,Song. Kyung-Sik,Seong. Yeon-Hee,Bae. Ki-Hwan
간행물명
韓國藥用作物學會誌
권/호정보
2006년|14권 5호|pp.267-272 (6 pages)
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한국약용작물학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Phytochemical study on the EtOAc fraction from the MeOH extract of the leaves of Cedrela sinensis led to the isolation of five known phenolic compounds (1-5), whose structures were identified as (+)-catechin (1), $kaempferol-3-0-{alpha}- L-rhamnopyranoside$ (2), quercetin (3), $quercetin-3-O-{alpha}-L-rhamnopyranoside$ (4), and $quercetin-3-O-{eta}-D-glucopyranoside$ (5), respectively, by comparing their spectral $(uv,;JR,;IH;and;^{13}C-NMR,;and;ESI-MS)$ and physicochemical data with those reported in the literature. Among the isolated compounds (1-5), compounds 1 and 3-5 exhibited significant DPPH radical scavenging effects with $IC{_50}$ values ranging from $21.3{pm}1.4;to;38.1{pm}3.2 {mu}M$ as well as superoxide anion radical scavenging effects with $IC{_50}$ values ranging from $9.4{pm}0.7;to;21.2{pm}3.6 {mu}M$. Furthermore, compounds 1 and 3-5 also exhibited considerable inhibitory effects on LDL peroxidation induced by either $CU^{2+}$ or AAPH with $IC{_50}$ values ranging from $1.4{pm}0.4;to;11.9{pm}1.4;{mu}M$. These results indicated that flavonoids are the major constituents of C. sinensis and considered to be antioxidant principles of this plant.