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서지반출
Novalis Shaped Beam Radiation Treatment for Craniopharyngiomas
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  • Novalis Shaped Beam Radiation Treatment for Craniopharyngiomas
  • Novalis Shaped Beam Radiation Treatment for Craniopharyngiomas
저자명
Yee. Gi-Taek,Han. Seong-Rok,Yoon. Sang-Won,Choi. Chan-Young,Lee. Dong-Joon,Whang. Choong-Jin
간행물명
Journal of Korean neurosurgical society
권/호정보
2006년|40권 4호|pp.245-248 (4 pages)
발행정보
대한신경외과학회
파일정보
정기간행물|ENG|
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기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Objective : To evaluate the effectiveness of Novalis shaped beam radiation treatment as an adjuvant treatment in patients with craniopharyngiomas. Methods : We reviewed 8 patients with craniopharyngiomas who had recurring tumors during follow-up or had residual lesions after primary surgery. Three of 8 patients were found to have recurrence after gross total excision of the tumor and 5 patents had residual lesions after subtotal resection. All patients were treated with fractionated stereotactic radiation treatment[FSRT] using Novalis system. The mean age of patients was 28 years [range $16{sim}52$]. The median irradiation dose per fraction was 17Gy [range $1.7{sim}2.0$]. The median fraction number was 23 [range $15{sim}25$], and the median total dose was 39.1 Gy [range $25.5{sim}42.5$]. Follow-up included MR imaging, and ophthalmologic and endocrine examinations. Results : The median follow-up period was 23 months [range $12{sim}43$]. The local tumor control rate was 87.5%. One patient had a recurring tumor, in which cystic change developed 2 months after FSRT. Four patients showed a decrease in size of their tumor, while 3 patients remained stable. Seven out of 8 patients had hormonal dysfunction that remained unchanged after initial surgery. No further progression of visual impairment was observed. Conclusion : FSRT using Novais system is effective and safe for the treatment of recurring or residual craniopharyngiomas without toxicity like optic neuropathy.