The thermo-mechanical analysis and test were performed for plate structure under mechanical and thermal loading conditions. Infrared heating system and hydraulic loading system were used to simulate mechanical and thermal environment for the plate structure which is similar to the fin of the airframe. Also, FEM analysis using plastic option was added to evaluate thermo-mechanical behavior. Thermo-mechanical tests were conducted at elevated temperature and rapid heating(10℃/sec) condition with external loading together. To investigate the effect of heating environment, the strength at room temperature was compared with that of elevated temperature and rapid heating condition. A methodology for test and analysis for supersonic vehicle subjected to aerodynamic loading and heating was generated through the study. These experimental and analysis results can be used for designing thermal resistance structures of the supersonic vehicle.