A critical speed analysis is performed for a 30 ton thrust turbopump considering the casing structural flexibility. A full three-dimensional finite element method including rotor and casing is used to predict rotordynamic behavior. Rotor alone model and rotor-casing coupled model with fixed-fixed and free-free boundary conditions are calculated to investigate the effects of the casing structural flexibility. The stiffness of ball bearings are applied as unloaded and loaded values to consider rotor operating conditions in vacuum and real engine respectively. From the results of the numerical analyses, it is found that the effect of the casing structural flexibility reduces the critical speeds of the turbopump. Especially, the loaded rotor condition with higher bearing stiffness is affected dramatically rather than the unloaded rotor condition with lower bearing stiffness.